Development and application of evolutionary algorithms
for the design of peptides
Wrede, P., Schneider, G., Schuchhardt, J.
Freie Universität Berlin, FB Humanmedizin, Institut für Med.-Tech. Physik und Lasermedizin, Krahmerstr. 6-10, D-12207 Berlin, Germany
Natural evolution deals with the permanent development of new peptide and protein sequences as a response to a changing enivironment. Since this process is very slow in comparison to the human life time the natural mechanisms finding new sequences are very elegant and obviously very reliable. The aim of our research is similar, namely finding new peptide sequences with a certain function but in a very short time! The main problem is to find appropiate models for the description of the sequence-activity relation (SAR). If such a model is available it will be easily possible to design peptides with certain functions or to predict the function of an amino acid sequence. Here some approaches to establish SAR-models for amino acid sequences are presented.
| LOCATION |
DATE |
TIME |
| Lecture Hall II |
Sunday, April 5 |
05:40 pm |