The mitochondrial genome in the context of the plant cell
Zabaleta E., Binder, S., Marchfelder, A., Knoop, V., Marienfeld, J., Unseld, M.,
Brandt, P., Giége P., Brennicke, A.
Abteilung Allgemeine Botanik der Universität Ulm, Albert-Einstein-Allee 11,
D-89069 Ulm, Germany
In the plant cell the three genomes in plastid, mitochondrion and nucleus have to be integrated and coordinately regulated. The mitochondrial genome, although generally much larger than the plastid genome, contains considerably less genes than the densely packed plastid DNA. Expression of the widely spaced mitochondrial genes thus requires individual transcription and translation signals for virtually every single coding region. Successful expression of these genes and their regulation involves particular transcription signals and is possibly regulated also at various steps of RNA maturation, such as processing, splicing, RNA editing and half-life-control. To establish functional mitochondrial enzymatic reaction chains, such as the complexes of the respiratory chain, expression of mitochondrial encoded genes has to be correlated with expression of the respective nuclear genes coding for polypeptides of these respective inner membrane complexes. Regulatory structures of nuclear genes are exemplary analyzed for several genes coding for subunits of complex I of the respiratory chain in plant mitochondria. Dissection and comparative analysis of promotor structures and regulatory elements of gene expression in mitochondrion and the nucleus show how integration and adaptation of genetic information encoded in two different genomes is functionally coordinated to create a cellular unit in plants.
| LOCATION |
DATE |
TIME |
| Lecture Hall I |
Monday, April 6 |
09:25 am |