A comprehensive theory of carcinogenesis and its reversal
Loefflmann, A.
Institute for Cancer Research and Treatment, Neuhauserstr. 25 /III, Munich, Germany
The epigenetic theory of carcinogenesis is discussed and a common triggering mechanism for carcinogenicity is elucidated for inorganic and organic compounds as well as for ionizing radiation at the site of carcinogenesis, in the mitochondria of the cell. Furthermore the specific properties of malignant cells, in particular the lactic acid production, are explained from bioenergetic point of view. It is demonstrated that the malignant cell imitates the genetic coding of the fertilized egg in a very early stage of gestation because of lack of energy. At the beginning in the embryonic cells energy is provided by anaerobic and aerobic glycolysis, because oxygen, only available by diffusion from surrounding air, is not sufficient for aerobic respiration in the mitochondria. In malignant cells we have the same terms if in more than eighty percent of mitochondria the cytochromoxydase is irreversibly blocked by one electron. Theoretical reflections faciliated the production of a causative acting substance - a metalloporphyrin Mr 67 kDalton, an oxygen evolving enzyme from photosynthetic apparatus from plants and protease inhibitors from fetal and embryonic tissue. This combined treatment is able to disintegrate chemical induced fibrosarcomas in rats and malignant cells in various human malignancies.
Loefflmann, A., Selective Antitumor Effects of Proteins Prepared from Photosystems of Plants and and Bovine Placentas and Bovine Umbilical Cords on 20- Methylcholantren Induced, Advanced Fibrosarcomas in Rats.
| LOCATION |
DATE |
TIME |
| Lecture Hall II |
Wednesday, April 8 |
09:00 am |